Penicillin V Potassium

Phenoxymethylpenicillin Potassium4 % PVP, granules, oral

Molecular formula:
C16H17N2O5S.K
Molecular weight:
388.5
CAS registry no.:
132-98-9
 Potassium

Application

Granules of Penicillin V Potassium and 4 % of povidone as a binding agent. The mixture is characterized by its excellent flowability and compressibility and can be used for different finished dosage forms after adding excipients.

Antibiotic category

Oral penicillin with reliable absorption

Packaging

Storage

Store below 25°C,
Protect from light and moisture

Shelf life

48 months

Specification

Appearancewhite to cream-coloured granules
Water content
(Karl Fischer)		not more than 0.7 %
pH-value5.0 - 7.5
4-Hydroxyphenoxymethylpenicillin potassium
(HPLC)		not more than 4.0 %
Largest impurity
(Ph.Eur./HPLC)		not more than 1.0 % 1)
AssayPenicillin V Potassium (HPLC):
91.0 - 96.0 %
1) The value of the largest peak referring to specified or unspecified by-products and degradation products, calculated as phenoxymethylpenicillin potassium

Pharmacopoeial quality

The active substance corresponds to USP, BP, Ph.Eur.